OCT Layers of The Retina
The vertebrate retina has ten distinct layers.[3] From closest to farthest from the vitreous body - that is, from closest to the front exterior of the head towards the interior and back of the head:
- Inner limiting membrane – basement membrane elaborated by Müller cells
- Nerve fibre layer – axons of the ganglion cell nuclei (note that a thin layer of Müller cell footplates exists between this layer and the inner limiting membrane)
- Ganglion cell layer – contains nuclei of ganglion cells, the axons of which become the optic nerve fibres for messages and some displaced amacrine cells
- Inner plexiform layer – contains the synapse between the bipolar cell axons and the dendrites of the ganglion and amacrine cells.
- Inner nuclear layer – contains the nuclei and surrounding cell bodies (perikarya) of the amacrine cells, bipolar cells and horizontal cells.
- Outer plexiform layer – projections of rods and cones ending in the rod spherule and cone pedicle, respectively. These make synapses with dendrites of bipolar cells.[1] In the macular region, this is known as the Fiber layer of Henle.
- Outer nuclear layer – cell bodies of rods and cones
- External limiting membrane – layer that separates the inner segment portions of the photoreceptors from their cell nucleus
- Layer of rods and cones – layer of rod cells and cone cells
- Retinal pigment epithelium - single layer of cuboidal cells (with extrusions not shown in diagram). This is closest to the choroid.
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